{"id":10659,"date":"2021-08-19T11:15:21","date_gmt":"2021-08-19T09:15:21","guid":{"rendered":"https:\/\/cidsr.md\/?post_type=news&#038;p=6520"},"modified":"2023-12-08T18:12:02","modified_gmt":"2023-12-08T15:12:02","slug":"crearea-unui-contraceptiv-masculin-reversibil-orientat-spre-testicule","status":"publish","type":"news","link":"https:\/\/cidsr.md\/ru\/news\/crearea-unui-contraceptiv-masculin-reversibil-orientat-spre-testicule\/","title":{"rendered":"\u0420\u0430\u0437\u0440\u0430\u0431\u043e\u0442\u043a\u0430 \u043e\u0431\u0440\u0430\u0442\u0438\u043c\u043e\u0433\u043e \u043c\u0443\u0436\u0441\u043a\u043e\u0433\u043e \u043a\u043e\u043d\u0442\u0440\u0430\u0446\u0435\u043f\u0442\u0438\u0432\u0430, \u0432\u043e\u0437\u0434\u0435\u0439\u0441\u0442\u0432\u0443\u044e\u0449\u0435\u0433\u043e \u043d\u0430 \u0442\u0435\u0441\u0442\u0438\u043a\u0443\u043b\u044b","raw":"\u0420\u0430\u0437\u0440\u0430\u0431\u043e\u0442\u043a\u0430 \u043e\u0431\u0440\u0430\u0442\u0438\u043c\u043e\u0433\u043e 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\u043c\u043e\u0433\u043b\u0438 \u0434\u0430\u0442\u044c \u043f\u043e\u0442\u043e\u043c\u0441\u0442\u0432\u043e, \u043d\u043e \u043d\u0430 60-\u0439 \u0434\u0435\u043d\u044c \u043e\u043d\u0438 \u0441\u043d\u043e\u0432\u0430 \u0441\u0442\u0430\u043b\u0438 \u0434\u0430\u0432\u0430\u0442\u044c \u043e\u043a\u043e\u043b\u043e 12 \u0434\u0435\u0442\u0435\u043d\u044b\u0448\u0435\u0439 \u043d\u0430 \u043e\u0434\u043d\u0443 \u0431\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u0443\u044e \u0441\u0430\u043c\u043a\u0443. \u041d\u0430\u043d\u043e\u0447\u0430\u0441\u0442\u0438\u0446\u044b \u0431\u044b\u043b\u0438 \u043d\u0435\u0442\u043e\u043a\u0441\u0438\u0447\u043d\u044b \u0434\u043b\u044f \u043a\u043b\u0435\u0442\u043e\u043a \u0438 \u043f\u043e\u0441\u0442\u0435\u043f\u0435\u043d\u043d\u043e \u0432\u044b\u0432\u043e\u0434\u0438\u043b\u0438\u0441\u044c \u0438\u0437 \u043e\u0440\u0433\u0430\u043d\u0438\u0437\u043c\u0430, \u0447\u0442\u043e \u043e\u0442\u043a\u0440\u044b\u0432\u0430\u0435\u0442 \u043d\u043e\u0432\u044b\u0435 \u0432\u043e\u0437\u043c\u043e\u0436\u043d\u043e\u0441\u0442\u0438 \u0434\u043b\u044f \u043c\u0443\u0436\u0441\u043a\u043e\u0439 \u043a\u043e\u043d\u0442\u0440\u0430\u0446\u0435\u043f\u0446\u0438\u0438, \u0443\u0442\u0432\u0435\u0440\u0436\u0434\u0430\u044e\u0442 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u0438.<\/p>\n<p><strong>\u0421\u0441\u044b\u043b\u043a\u0430:<\/strong>\u00a0\u0412.\u0414\u0438\u043d\u0433, \u0416.\u0427\u0435\u043d, \u042f.\u0413\u0443, \u0416.\u0427\u0435\u043d, \u042f.\u0416\u0435\u043d\u0433, \u0424.\u0421\u0430\u043d. \u041c\u0430\u0433\u043d\u0438\u0442\u043d\u043e\u0435 \u043d\u0430\u0446\u0435\u043b\u0438\u0432\u0430\u043d\u0438\u0435 \u043d\u0430 \u0442\u0435\u0441\u0442\u0438\u043a\u0443\u043b\u044b \u0438 \u043c\u0430\u0433\u043d\u0438\u0442\u043d\u0430\u044f \u0433\u0438\u043f\u0435\u0440\u0442\u0435\u0440\u043c\u0438\u044f \u0434\u043b\u044f \u043d\u0435\u0438\u043d\u0432\u0430\u0437\u0438\u0432\u043d\u043e\u0439 \u043a\u043e\u043d\u0442\u0440\u043e\u043b\u0438\u0440\u0443\u0435\u043c\u043e\u0439 \u043c\u0443\u0436\u0441\u043a\u043e\u0439 \u043a\u043e\u043d\u0442\u0440\u0430\u0446\u0435\u043f\u0446\u0438\u0438 \u043f\u0443\u0442\u0435\u043c \u0432\u043d\u0443\u0442\u0440\u0438\u0432\u0435\u043d\u043d\u043e\u0433\u043e \u0432\u0432\u0435\u0434\u0435\u043d\u0438\u044f. <em>Nano Lett<\/em>. 2021;21(14):6289-6297. doi: <u><a href=\"https:\/\/doi.org\/10.1021\/acs.nanolett.1c02181\">10.1021\/acs.nanolett.1c02181<\/a><\/u><\/p>\n[:]\n","protected":false,"raw":"\n\n<span style=\"font-size: 10pt;\"><img src=\"https:\/\/cidsr.md\/wp-content\/uploads\/2021\/08\/Controllable-Male-Contraception-via-Intravenous-Administration.gif\" alt=\"\" class=\"alignright size-full wp-image-6521\" width=\"500\" height=\"267\" \/>29 \u0438\u044e\u043b\u044f 2021 \u0433\u043e\u0434\u0430\u00a0|\u00a0<u><a href=\"https:\/\/www.technologynetworks.com\/drug-discovery\/go\/lc\/view-source-351403\">\u041e\u0440\u0438\u0433\u0438\u043d\u0430\u043b\u044c\u043d\u0430\u044f \u0438\u0441\u0442\u043e\u0440\u0438\u044f \u043e\u0442 \u0410\u043c\u0435\u0440\u0438\u043a\u0430\u043d\u0441\u043a\u043e\u0433\u043e \u0445\u0438\u043c\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u043e\u0431\u0449\u0435\u0441\u0442\u0432\u0430<\/a><\/u><\/span>\n\n\u0423 \u0436\u0435\u043d\u0449\u0438\u043d \u0435\u0441\u0442\u044c \u0432\u044b\u0431\u043e\u0440 \u043c\u0435\u0436\u0434\u0443 \u0434\u043e\u043b\u0433\u043e\u0441\u0440\u043e\u0447\u043d\u044b\u043c\u0438 \u0438 \u043e\u0431\u0440\u0430\u0442\u0438\u043c\u044b\u043c\u0438 \u043a\u043e\u043d\u0442\u0440\u0430\u0446\u0435\u043f\u0442\u0438\u0432\u0430\u043c\u0438, \u043d\u043e \u0434\u043b\u044f \u043c\u0443\u0436\u0447\u0438\u043d \u0431\u043e\u043b\u044c\u0448\u0438\u043d\u0441\u0442\u0432\u043e \u0432\u0430\u0440\u0438\u0430\u043d\u0442\u043e\u0432 \u043b\u0438\u0431\u043e \u043e\u0434\u043d\u043e\u0440\u0430\u0437\u043e\u0432\u044b\u0435, \u043a\u0430\u043a \u043f\u0440\u0435\u0437\u0435\u0440\u0432\u0430\u0442\u0438\u0432\u044b, \u043b\u0438\u0431\u043e \u0442\u0440\u0443\u0434\u043d\u043e \u043e\u0431\u0440\u0430\u0442\u0438\u043c\u044b\u0435, \u043a\u0430\u043a \u0432\u0430\u0437\u044d\u043a\u0442\u043e\u043c\u0438\u044f. \u0422\u0435\u043f\u0435\u0440\u044c, \u0434\u0435\u043b\u0430\u044f \u0448\u0430\u0433 \u043a \u0441\u043e\u0437\u0434\u0430\u043d\u0438\u044e \u0431\u0435\u0437\u043e\u043f\u0430\u0441\u043d\u043e\u0433\u043e, \u0434\u043e\u043b\u0433\u043e\u0441\u0440\u043e\u0447\u043d\u043e\u0433\u043e \u0438 \u043e\u0431\u0440\u0430\u0442\u0438\u043c\u043e\u0433\u043e \u043c\u0443\u0436\u0441\u043a\u043e\u0433\u043e \u043a\u043e\u043d\u0442\u0440\u0430\u0446\u0435\u043f\u0442\u0438\u0432\u0430, \u043f\u0443\u0431\u043b\u0438\u043a\u0443\u044e\u0449\u0438\u0435\u0441\u044f \u0432 \u0436\u0443\u0440\u043d\u0430\u043b\u0435 \u0410\u043c\u0435\u0440\u0438\u043a\u0430\u043d\u0441\u043a\u043e\u0433\u043e \u0445\u0438\u043c\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u0441\u043e\u043e\u0431\u0449\u0435\u0441\u0442\u0432\u0430 (ACS) <em>Nano Letters<\/em> \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u0438 \u0440\u0430\u0437\u0440\u0430\u0431\u043e\u0442\u0430\u043b\u0438 \u043c\u0430\u0433\u043d\u0438\u0442\u043d\u044b\u0435, \u0431\u0438\u043e\u0440\u0430\u0437\u043b\u0430\u0433\u0430\u0435\u043c\u044b\u0435 \u043d\u0430\u043d\u043e\u043c\u0430\u0442\u0435\u0440\u0438\u0430\u043b\u044b, \u0441\u043d\u0438\u0436\u0430\u044e\u0449\u0438\u0435 \u0432\u0435\u0440\u043e\u044f\u0442\u043d\u043e\u0441\u0442\u044c \u0437\u0430\u0447\u0430\u0442\u0438\u044f \u043f\u043e\u0442\u043e\u043c\u0441\u0442\u0432\u0430 \u0443 \u043c\u044b\u0448\u0435\u0439 \u043f\u043e \u043a\u0440\u0430\u0439\u043d\u0435\u0439 \u043c\u0435\u0440\u0435 \u043d\u0430 30 \u0434\u043d\u0435\u0439.\n\n\u041f\u043e\u0432\u044b\u0448\u0435\u043d\u043d\u0430\u044f \u0442\u0435\u043c\u043f\u0435\u0440\u0430\u0442\u0443\u0440\u0430, \u043a\u043e\u0442\u043e\u0440\u0430\u044f \u043c\u043e\u0436\u0435\u0442 \u0431\u044b\u0442\u044c \u0432\u044b\u0437\u0432\u0430\u043d\u0430 \u043d\u043e\u0448\u0435\u043d\u0438\u0435\u043c \u0441\u043b\u0438\u0448\u043a\u043e\u043c \u0442\u0435\u0441\u043d\u044b\u0445 \u0431\u0440\u044e\u043a \u0438\u043b\u0438 \u043d\u0438\u0436\u043d\u0435\u0433\u043e \u0431\u0435\u043b\u044c\u044f, \u043c\u043e\u0436\u0435\u0442 \u0441\u043d\u0438\u0437\u0438\u0442\u044c \u043a\u043e\u043b\u0438\u0447\u0435\u0441\u0442\u0432\u043e \u0441\u043f\u0435\u0440\u043c\u0430\u0442\u043e\u0437\u043e\u0438\u0434\u043e\u0432 \u0443 \u043c\u0443\u0436\u0447\u0438\u043d. \u041d\u0435\u043a\u043e\u0442\u043e\u0440\u044b\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u0438 \u0438\u0437\u0443\u0447\u0438\u043b\u0438 \u0431\u043e\u043b\u0435\u0435 \u0438\u043d\u0442\u0435\u043d\u0441\u0438\u0432\u043d\u044b\u0439 \u043d\u0430\u0433\u0440\u0435\u0432 \u043d\u0430\u043d\u043e\u043c\u0430\u0442\u0435\u0440\u0438\u0430\u043b\u043e\u0432, \u0432\u0432\u043e\u0434\u0438\u043c\u044b\u0445 \u0432 \u0442\u0435\u0441\u0442\u0438\u043a\u0443\u043b\u044b, \u043a\u0430\u043a \u0444\u043e\u0440\u043c\u0443 \u043c\u0443\u0436\u0441\u043a\u043e\u0433\u043e \u043a\u043e\u043d\u0442\u0440\u0430\u0446\u0435\u043f\u0442\u0438\u0432\u043d\u043e\u0433\u043e \u0441\u0440\u0435\u0434\u0441\u0442\u0432\u0430. \u041e\u0434\u043d\u0430\u043a\u043e \u0438\u043d\u044a\u0435\u043a\u0446\u0438\u0438 \u043c\u043e\u0433\u0443\u0442 \u0431\u044b\u0442\u044c \u0431\u043e\u043b\u0435\u0437\u043d\u0435\u043d\u043d\u044b\u043c\u0438, \u043d\u0430\u0433\u0440\u0435\u0432 \u043c\u043e\u0436\u0435\u0442 \u043f\u043e\u0432\u0440\u0435\u0434\u0438\u0442\u044c \u043a\u043e\u0436\u0443, \u0430 \u0431\u043e\u043b\u044c\u0448\u0438\u043d\u0441\u0442\u0432\u043e \u0438\u0441\u043f\u044b\u0442\u0430\u043d\u043d\u044b\u0445 \u043d\u0430 \u0441\u0435\u0433\u043e\u0434\u043d\u044f\u0448\u043d\u0438\u0439 \u0434\u0435\u043d\u044c \u043d\u0430\u043d\u043e\u043c\u0430\u0442\u0435\u0440\u0438\u0430\u043b\u043e\u0432 \u043d\u0435 \u043f\u043e\u0434\u0434\u0430\u044e\u0442\u0441\u044f \u0431\u0438\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u043e\u043c\u0443 \u0440\u0430\u0437\u043b\u043e\u0436\u0435\u043d\u0438\u044e. \u0412\u0430\u0439\u0443\u0430 \u0414\u0438\u043d\u0433, \u0424\u0435\u0439 \u0421\u0430\u043d \u0438 \u0438\u0445 \u043a\u043e\u043b\u043b\u0435\u0433\u0438 \u0445\u043e\u0442\u0435\u043b\u0438 \u0440\u0430\u0437\u0440\u0430\u0431\u043e\u0442\u0430\u0442\u044c \u0431\u0435\u0437\u043e\u043f\u0430\u0441\u043d\u044b\u0439 \u0438 \u044d\u0444\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u044b\u0439 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\u043d\u0430 \u0442\u0435\u0441\u0442\u0438\u043a\u0443\u043b\u044b \u0438 \u043c\u0430\u0433\u043d\u0438\u0442\u043d\u0430\u044f \u0433\u0438\u043f\u0435\u0440\u0442\u0435\u0440\u043c\u0438\u044f \u0434\u043b\u044f \u043d\u0435\u0438\u043d\u0432\u0430\u0437\u0438\u0432\u043d\u043e\u0439 \u043a\u043e\u043d\u0442\u0440\u043e\u043b\u0438\u0440\u0443\u0435\u043c\u043e\u0439 \u043c\u0443\u0436\u0441\u043a\u043e\u0439 \u043a\u043e\u043d\u0442\u0440\u0430\u0446\u0435\u043f\u0446\u0438\u0438 \u043f\u0443\u0442\u0435\u043c \u0432\u043d\u0443\u0442\u0440\u0438\u0432\u0435\u043d\u043d\u043e\u0433\u043e \u0432\u0432\u0435\u0434\u0435\u043d\u0438\u044f. <em>Nano Lett<\/em>. 2021;21(14):6289-6297. doi: <u><a href=\"https:\/\/doi.org\/10.1021\/acs.nanolett.1c02181\">10.1021\/acs.nanolett.1c02181<\/a><\/u>\n\n[:]\n\n"},"excerpt":{"rendered":"","protected":false,"raw":""},"author":4,"featured_media":6521,"parent":0,"template":"page-news-details.php","blog_news":[],"class_list":["post-10659","news","type-news","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Crearea unui contraceptiv masculin reversibil orientat spre testicule - Centrul de Instruire \u00een Domeniul S\u0103n\u0103t\u0103\u0163ii Reproductive<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cidsr.md\/%news-slug%\/crearea-unui-contraceptiv-masculin-reversibil-orientat-spre-testicule\/\" \/>\n<meta property=\"og:locale\" content=\"ru_RU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Crearea unui contraceptiv masculin reversibil orientat spre testicule - Centrul de Instruire \u00een Domeniul S\u0103n\u0103t\u0103\u0163ii Reproductive\" \/>\n<meta property=\"og:description\" content=\"29 \u0438\u044e\u043b\u044f 2021 \u0433\u043e\u0434\u0430\u00a0|\u00a0\u041e\u0440\u0438\u0433\u0438\u043d\u0430\u043b\u044c\u043d\u0430\u044f \u0438\u0441\u0442\u043e\u0440\u0438\u044f \u043e\u0442 \u0410\u043c\u0435\u0440\u0438\u043a\u0430\u043d\u0441\u043a\u043e\u0433\u043e \u0445\u0438\u043c\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u043e\u0431\u0449\u0435\u0441\u0442\u0432\u0430 \u0423 \u0436\u0435\u043d\u0449\u0438\u043d \u0435\u0441\u0442\u044c \u0432\u044b\u0431\u043e\u0440 \u043c\u0435\u0436\u0434\u0443 \u0434\u043e\u043b\u0433\u043e\u0441\u0440\u043e\u0447\u043d\u044b\u043c\u0438 \u0438 \u043e\u0431\u0440\u0430\u0442\u0438\u043c\u044b\u043c\u0438 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\u043e\u0431\u0440\u0430\u0442\u0438\u043c\u043e\u0433\u043e \u043c\u0443\u0436\u0441\u043a\u043e\u0433\u043e \u043a\u043e\u043d\u0442\u0440\u0430\u0446\u0435\u043f\u0442\u0438\u0432\u0430, \u043f\u0443\u0431\u043b\u0438\u043a\u0443\u044e\u0449\u0438\u0435\u0441\u044f \u0432 \u0436\u0443\u0440\u043d\u0430\u043b\u0435 \u0410\u043c\u0435\u0440\u0438\u043a\u0430\u043d\u0441\u043a\u043e\u0433\u043e \u0445\u0438\u043c\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u0441\u043e\u043e\u0431\u0449\u0435\u0441\u0442\u0432\u0430 (ACS) Nano Letters \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u0438 \u0440\u0430\u0437\u0440\u0430\u0431\u043e\u0442\u0430\u043b\u0438 \u043c\u0430\u0433\u043d\u0438\u0442\u043d\u044b\u0435, [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cidsr.md\/%news-slug%\/crearea-unui-contraceptiv-masculin-reversibil-orientat-spre-testicule\/\" \/>\n<meta property=\"og:site_name\" content=\"Centrul de Instruire \u00een Domeniul 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\u0441\u043e\u0437\u0434\u0430\u043d\u0438\u044e \u0431\u0435\u0437\u043e\u043f\u0430\u0441\u043d\u043e\u0433\u043e, \u0434\u043e\u043b\u0433\u043e\u0441\u0440\u043e\u0447\u043d\u043e\u0433\u043e \u0438 \u043e\u0431\u0440\u0430\u0442\u0438\u043c\u043e\u0433\u043e \u043c\u0443\u0436\u0441\u043a\u043e\u0433\u043e \u043a\u043e\u043d\u0442\u0440\u0430\u0446\u0435\u043f\u0442\u0438\u0432\u0430, \u043f\u0443\u0431\u043b\u0438\u043a\u0443\u044e\u0449\u0438\u0435\u0441\u044f \u0432 \u0436\u0443\u0440\u043d\u0430\u043b\u0435 \u0410\u043c\u0435\u0440\u0438\u043a\u0430\u043d\u0441\u043a\u043e\u0433\u043e \u0445\u0438\u043c\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u0441\u043e\u043e\u0431\u0449\u0435\u0441\u0442\u0432\u0430 (ACS) Nano Letters \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u0438 \u0440\u0430\u0437\u0440\u0430\u0431\u043e\u0442\u0430\u043b\u0438 \u043c\u0430\u0433\u043d\u0438\u0442\u043d\u044b\u0435, 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testicule"}]},{"@type":"WebSite","@id":"https:\/\/cidsr.md\/#website","url":"https:\/\/cidsr.md\/","name":"Centrul de Instruire \u00een Domeniul S\u0103n\u0103t\u0103\u0163ii Reproductive","description":"Promov\u0103m s\u0103n\u0103tatea \u0219i drepturile sexuale \u0219i reproductive!","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/cidsr.md\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"ru-RU"}]}},"meta":{"_en_post_content":"\n\n<span style=\"font-size: 10pt;\"><img src=\"https:\/\/cidsr.md\/wp-content\/uploads\/2021\/08\/Controllable-Male-Contraception-via-Intravenous-Administration.gif\" alt=\"\" class=\"alignright size-full wp-image-6521\" width=\"500\" height=\"267\" \/>July 29 2021\u00a0|\u00a0<\/span><u><a href=\"https:\/\/www.technologynetworks.com\/drug-discovery\/go\/lc\/view-source-351403\"><span style=\"font-size: 10pt;\">Original story from American Chemical Society<\/span><\/a><\/u>\n\nWomen have several choices for long-lasting, reversible contraceptives, but most options for men are either single-use, such as condoms, or difficult to reverse, like vasectomies. Now, in a step toward a safe, long-lasting and reversible male contraceptive, researchers reporting in ACS\u2019\u00a0<em>Nano Letters<\/em>\u00a0have developed magnetic, biodegradable nanomaterials that reduced the likelihood of mice fathering pups for at least 30 days.\n\nElevated temperatures, which can be caused by wearing too-tight pants or underwear, can decrease sperm count in men. Some researchers have explored the more intense heating of nanomaterials injected into the testes as a form of male birth control. However, the injection can be painful, the heating can damage skin, and most nanomaterials tested so far are not biodegradable. Weihua Ding, Fei Sun and colleagues wanted to develop a safe, effective magnetic-thermal approach to male contraception that doesn\u2019t need to be injected directly into the testes.\n\nThe researchers tested two forms of iron oxide nanoparticles, which are biodegradable and can be guided and heated with magnetic fields, as male contraceptives. One type of nanoparticle was coated with polyethylene glycol (PEG) and the other with citric acid. Although the PEG-coated nanoparticles could be heated to higher temperatures, they were not as easily manipulated by magnets as the other ones. So the researchers injected repeated doses of citric acid-coated nanoparticles into the bloodstream of mice for 2 days, guided the nanomaterials to the testes with magnets, and then applied an alternating magnetic field to the area for 15 minutes. The nanoparticles heated the testes to a temperature of 104 F, shrinking them and inhibiting spermatogenesis before gradual recovery 30 to 60 days after treatment. The mice couldn\u2019t father any pups 7 days after treatment, but they were back to fathering about 12 pups per pregnant female at day 60. The nanoparticles were non-toxic to cells and were gradually eliminated from the body, offering new possibilities for male contraception, the researchers say.\n\n<strong>Reference:<\/strong>\u00a0Ding W, Chen Z, Gu Y, Chen Z, Zheng Y, Sun F. Magnetic testis targeting and magnetic hyperthermia for noninvasive, controllable male contraception via intravenous administration. <em>Nano Lett<\/em>. 2021;21(14):6289-6297. doi: <u><a href=\"https:\/\/doi.org\/10.1021\/acs.nanolett.1c02181\">10.1021\/acs.nanolett.1c02181<\/a><\/u>\n\n[:][:]","_en_post_excerpt":"","_en_post_title":"Designing a Reversible Male Contraceptive Targeted to the Testes[:]","_en_post_name":"crearea-unui-contraceptiv-masculin-reversibil-orientat-spre-testicule","_ro_post_content":"\n\n<span style=\"font-size: 10pt;\"><img src=\"https:\/\/cidsr.md\/wp-content\/uploads\/2021\/08\/Controllable-Male-Contraception-via-Intravenous-Administration.gif\" alt=\"\" class=\"alignright size-full wp-image-6521\" width=\"500\" height=\"267\" \/>29 iulie 2021 |\u00a0<u><a href=\"https:\/\/www.technologynetworks.com\/drug-discovery\/go\/lc\/view-source-351403\">Istorie original\u0103 de la American Chemical Society<\/a><\/u><\/span>\n\nFemeile au mai multe op\u021biuni de contraceptive reversibile de lung\u0103 durat\u0103, \u00een timp ce majoritatea op\u021biunilor pentru b\u0103rba\u021bi sunt fie de unic\u0103 folosin\u021b\u0103, cum ar fi prezervativele, fie dificil de inversat, precum vasectomiile. Acum, drept un pas \u00een direc\u021bia unui contraceptiv masculin sigur, de lung\u0103 durat\u0103 \u0219i reversibil, cercet\u0103torii raporteaz\u0103 \u00een\u00a0<em>Nano Letters<\/em>\u00a0produs de ACS c\u0103 au dezvoltat nanomateriale magnetice, biodegradabile, care au redus probabilitatea ca \u0219oarecii s\u0103 nasc\u0103 pui timp de cel pu\u021bin 30 de zile.\n\nTemperaturile ridicate ce pot fi cauzate de purtarea pantalonilor sau lenjeriei prea str\u00e2mte, pot reduce cantitatea spermei la b\u0103rba\u021bi. Unii cercet\u0103tori au explorat \u00eenc\u0103lzirea mai intens\u0103 a nanomaterialelor injectate \u00een testicule ca form\u0103 de control al procre\u0103rii la b\u0103rba\u021bi. Cu toate acestea, injec\u021bia poate fi dureroas\u0103, \u00eenc\u0103lzirea poate deteriora pielea, iar majoritatea nanomaterialelor testate p\u00e2n\u0103 acum nu sunt biodegradabile. Weihua Ding, Fei Sun \u0219i colegii au dorit s\u0103 dezvolte o abordare magnetic\u0103-termic\u0103 sigur\u0103 \u0219i eficient\u0103 a contracep\u021biei masculine, care nu trebuie s\u0103 fie injectat\u0103 direct \u00een testicule.\n\nCercet\u0103torii au testat dou\u0103 forme de nanoparticule de oxid de fier, care sunt biodegradabile \u0219i pot fi ghidate \u0219i \u00eenc\u0103lzite cu c\u00e2mpuri magnetice, \u00een calitate de contraceptive masculine. Un tip de nanoparticule a fost acoperit cu polietilenglicol (PEG), iar cel\u0103lalt cu acid citric. De\u0219i nanoparticulele acoperite cu PEG au putut fi \u00eenc\u0103lzite la temperaturi mai mari, ele nu au putut fi manipulate la fel de u\u0219or de magne\u021bi ca celelalte. Astfel, cercet\u0103torii au injectat doze repetate de nanoparticule acoperite cu acid citric \u00een s\u00e2ngele \u0219oarecilor timp de 2 zile, au ghidat nanomaterialele spre testicule cu ajutorul magne\u021bilor, apoi au aplicat un c\u00e2mp magnetic alternativ pe zona respectiv\u0103 timp de 15 minute. Nanoparticulele au \u00eenc\u0103lzit testiculele la o temperatur\u0103 de 104<sup>0<\/sup> F, mic\u0219or\u00e2ndu-le \u0219i inhib\u00e2nd spermatogeneza \u00eenainte de recuperarea treptat\u0103 la 30-60 de zile dup\u0103 tratament. \u0218oarecii nu au putut concepe niciun pui 7 zile dup\u0103 tratament, dar au putut concepe aproximativ 12 pui per femel\u0103 gravid\u0103 \u00een ziua a 60-a. Nanoparticulele au fost non-toxice pentru celule \u0219i au fost eliminate treptat din organism, oferind posibilit\u0103\u021bi noi de contracep\u021bie masculin\u0103, afirm\u0103 cercet\u0103torii.\n\n<strong>Referin\u021b\u0103:<\/strong>\u00a0Ding W, Chen Z, Gu Y, Chen Z, Zheng Y, Sun F. Direc\u021bionarea magnetic\u0103 a testiculelor \u0219i hipertermia magnetic\u0103 pentru contracep\u021bia masculin\u0103 neinvaziv\u0103 \u0219i controlabil\u0103 prin administrare intravenoas\u0103. <em>Nano Lett<\/em>. 2021;21(14):6289-6297. doi: <u><a href=\"https:\/\/doi.org\/10.1021\/acs.nanolett.1c02181\">10.1021 \/ acs.nanolett.1c02181<\/a><\/u>\n\n\n\n","_ro_post_excerpt":"","_ro_post_title":"Crearea unui contraceptiv masculin reversibil orientat spre testicule","_ro_post_name":"crearea-unui-contraceptiv-masculin-reversibil-orientat-spre-testicule","edit_language":"ru"},"_links":{"self":[{"href":"https:\/\/cidsr.md\/ru\/wp-json\/wp\/v2\/news\/10659","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cidsr.md\/ru\/wp-json\/wp\/v2\/news"}],"about":[{"href":"https:\/\/cidsr.md\/ru\/wp-json\/wp\/v2\/types\/news"}],"author":[{"embeddable":true,"href":"https:\/\/cidsr.md\/ru\/wp-json\/wp\/v2\/users\/4"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cidsr.md\/ru\/wp-json\/"}],"wp:attachment":[{"href":"https:\/\/cidsr.md\/ru\/wp-json\/wp\/v2\/media?parent=10659"}],"wp:term":[{"taxonomy":"blog_news","embeddable":true,"href":"https:\/\/cidsr.md\/ru\/wp-json\/wp\/v2\/blog_news?post=10659"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}